Database for Stroke in Infants and Children: the International Pediatric Stroke Study
Recruiting now NCT00084292
Run by The Hospital for Sick Children · for Up to 18 · All sexes
What this study is about
The International Pediatric Stroke Study (IPSS) was established in 2003 as a multi-center, multi-national clinical research registry. Over the years, it has grown to become a highly successful study vehicle for pediatric stroke research across over 100 institutions worldwide. Today, The IPSS continues to serve as the global clinical data and imaging core for multi-disciplinary pediatric experts who perform international collaborative research to better understand, prevent, and improve outcomes in pediatric stroke. The robust dataset and cohesive network enable high caliber and ground-breaking research in the field. Participating sites enroll neonates or children who have had an ischemic or hemorrhagic stroke, or may be at high risk of having a stroke. Participants have their medical and research records reviewed for information about their stroke and abstracted into a secure electronic database called REDCap, which is hosted at SickKids in Toronto Canada. The IPSS also provides an attractive imaging platform (through the Stroke Imaging Lab for Children, SILC, housed at SickKids) for sites to share clinically acquired brain images that will complement the clinical dataset. The clinical and imaging datasets will improve our understanding of the processes underlying plasticity and recovery in childhood stroke.
Who can join (things the study team will check)
✅ You may be able to join if…
- Arterial Ischemic Stroke (AIS),
- Cerebral Sinovenous Thrombosis (CSVT),
- AIS and CSVT
- Presume Preinatal Ischemic Stroke (PPIS)
- Children diagnosed with hemorrhagic stroke Children at high risk of stroke include:
- Those diagnosed with arteriopathy, arteritis/vasculitis, moyamoya, dissection, sickle cell related infarcts).
- Brain arteriovenous malformations
🚫 You may not be able to join if…
- Premature children diagnosed with AIS.
- Premature children diagnosed with PPIS
- Children diagnosed with TIA (Transient Ischemic Attack)
- Brain hemorrhage secondary to trauma
- Refusal to provide consent for participation
Where this trial is running
- Hospital For Sick Children, Toronto, Ontario, Canada
Who to contact
IPSS Central · 416-813-7654 · ipss.research@sickkids.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT00084292.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.