Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study
Recruiting now NCT02678884
Run by University Health Network, Toronto · for 18 and older · All sexes
What this study is about
The purpose of this study is to see how useful the information provided from Positron Emission Tomography (PET) scans can be in the actual planning and delivery of radiation treatment to patients who have head and neck cancers. Patients participating in this study, will have (in addition to their routine tests) a PET scan before and during their radiation treatment. Following the intervention, patients will be followed as per standard practice.
Who can join (things the study team will check)
✅ You may be able to join if…
- Non-nasopharynx head and neck mucosal squamous cell carcinoma
- Radiologically evident gross disease
- Radiotherapy alone for curative intent
- Age equal to or more than 18 years old
- To be eligible for the second study PET-CT scan: FDG avid tumour (or minimum SUV of 2.5) on the first study PET-CT scan
🚫 You may not be able to join if…
- Nasopharynx cancer
- H\&N SCC skin
- Distant metastases (already known or if found on baseline CT-thorax)
- Prior malignancy within the last 5 years (exclude non-H\&N SCC, BCC skin)
- Prior chemotherapy within the last 5 years or concurrent chemotherapy/EGFR inhibitors
- Prior head and neck radiotherapy
- Inability to lie supine for study duration
- Pregnancy
- Inability to provide informed consent
Where this trial is running
- University Health Network, Princess Margaret Cancer Center, Toronto, Ontario, Canada
Who to contact
John J Kim, MD · 416 946 4501 · John.kim@rmp.uhn.on.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT02678884.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.