Bright Ideas - CIN Feasibility Study
Recruiting now NCT04929899
Run by The Hospital for Sick Children · for 4 to 18 · All sexes
What this study is about
In this study investigators will determine the feasibility of a future trial comparing chemotherapy-induced nausea control in children with ALL receiving oral 6-mercaptopurine who do and do not receive problem-solving skill training. This is a novel approach to controlling an important and common treatment-related symptom.
Who can join (things the study team will check)
✅ You may be able to join if…
- Age: ≥ 4 years (PeNAT validated in patients 4 to 18 yrs)
- newly diagnosed or recurrent disease: first diagnosis of ALL (i.e. non-relapsed) in maintenance therapy
- English, French or Spanish-speaking with an English, French or Spanish-speaking guardian (PeNAT available in these languages)
- without physical or cognitive impairments that preclude use of the PeNAT
- planned to receive PO 6-mercaptopurine
- not planned to receive IV, IM, SC or IT chemotherapy or oral or IV corticosteroids during the 7-day study period
Where this trial is running
- Children's Hospital Los Angeles, Los Angeles, California, United States
- Rutgers Cancer Institute, New Brunswick, New Jersey, United States
- Inova Children's Hospital, Falls Church, Virginia, United States
- Hospital for Sick Children, Toronto, Ontario, Canada
Who to contact
Lee Dupuis, PhD · 416-813-7762 · lee.dupuis@sickkids.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT04929899.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.
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