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Optimal Management of Extreme Obesity and Severe Knee Osteoarthritis Feasibility Trial

Recruiting now NCT05120492

Run by Nova Scotia Health Authority ยท for 18 to 65 ยท All sexes ยท accepts healthy volunteers

What this study is about

Does weight loss surgery in patients with morbid obesity prior to knee replacement surgery improve outcomes from knee replacement surgery

Who can join (things the study team will check)

Inclusion Criteria: severe knee osteoarthritis body-mass index of 45 to 60 Exclusion Criteria: previous total replacement of the same knee, a need for bilateral total knee replacement, and knee pain during the previous week that the patient rated at higher than 60 mm on a 100-mm visual-analogue scale. Also,prior bariatric or complex foregut surgery, significant cardiovascular, pulmonary, renal, liver, gastrointestinal, psychiatric disorders, pregnancy, malignancy within last 5 years, anemia, coagulopathy requiring anti-coagulation therapy.โ€ฆ

Where this trial is running

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Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.

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