Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes

What this study is about

Participants will be asked to wear a continuous glucose monitor for at least three days on three separate occasions. One testing session will be a no-exercise resting control session (90 minutes). One will be a moderate aerobic exercise session (30 minutes of exercise, 60 minutes of recovery), and the third will be a moderate weight-lifting session (\~30 minutes of exercise, 60 minutes of recovery).The investigators will measure changes in blood glucose during exercise by drawing blood during and after exercise. Post-exercise glucose trends will be examined using continuous glucose monitoring.

Who can join (things the study team will check)

✅ You may be able to join if…

• type 1 diabetes, diagnosed for at least one year
• post-menopause (at least one year since last menstrual period), or have had a hysterectomy and bilateral salpingo oophorectomy
• able to perform aerobic and resistance exercise
• able to visit the lab in Edmonton, Alberta (University of Alberta)

🚫 You may not be able to join if…

• HbA1c > 9.9 %
• frequent and unpredictable hypoglycemia
• change in insulin management strategy within the last 2 months
• blood pressure > 140 / 95
• severe peripheral neuropathy
• history of cardiovascular disease
• musculoskeletal injuries interfering with exercise performance
• use of medications (other than insulin) that affect glucose metabolism
• BMI > 30 kg/m2
• smoking
• moderate to high alcohol intake (> 2 drinks/day)

Where this trial is running

• Alberta Diabetes Institute, Edmonton, Alberta, Canada
• Institut de recherches cliniques de Montréal, Montreal, Quebec, Canada

Who to contact

Jane E Yardley, PhD · 780-679-1688 · jane.yardley@ualberta.ca

It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT05188027.