Canadian Observational Study Evaluating the Long-term IMPACT of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators on People With CF
Recruiting now NCT05200429
Run by University of British Columbia · for All ages · All sexes
What this study is about
This observational study intends to investigate health trends and data in cystic fibrosis patients all across Canada that are receiving modulator treatment so researchers can determine if CFTR treatments are effective over a long period of time and if so, which treatments work best for each individual. The study will collect clinical data from routine standard of care, patient reported outcomes via survey data and samples for a biobank.
Who can join (things the study team will check)
✅ You may be able to join if…
- Prescribed a CFTR modulator therapy and planning to commence modulator therapy within 30 days OR planning to switch modulator therapies within 30 days
- Participates in the Canadian Cystic Fibrosis Registry (CCFR)
- Informed consent by participant, or parent/legal guardian or assent
🚫 You may not be able to join if…
- Known contraindications to CFTR modulator therapy
Where this trial is running
- British Columbia Children's Hospital, Vancouver, British Columbia, Canada
- St Paul's Hospital, Vancouver, British Columbia, Canada
Who to contact
Alam Lakhani · 604-875-2345 · alam.lakhani@cw.bc.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT05200429.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.