Micro-UltraSound In Cancer - Active Surveillance
Recruiting now NCT05558241
Run by University of Alberta · for 18 and older · Men
What this study is about
This study will compare the two imaging modalities (MRI and micro-ultrasound) during Active Surveillance of prostate cancer (PCa). Progression to clinically significant PCa will be assessed by first taking micro-US targeted samples (while blinded to MRI results), followed by MRI targeted samples, finishing with 12 systematic biopsy cores. The primary goal is to compare microUS to MRI for the detection of ≥GG2 PCa at confirmatory biopsy. This study will also collect blood samples from participants to be used for future biomarker studies.
Who can join (things the study team will check)
✅ You may be able to join if…
- Adult men with Gleason Grade Group 1 prostate cancer managed by active surveillance who require a confirmatory prostate biopsy
🚫 You may not be able to join if…
- Men who cannot undergo a prostate MRI
- Men who cannot undergo a prostate biopsy
Where this trial is running
- University of California Los Angeles, Department of Urology, Los Angeles, California, United States
- Kipnes Urology Centre - Kaye Edmonton Clinic, Edmonton, Alberta, Canada
- University of British Columbia, Vancouver, Alberta, Canada
- CIUSSS du Nord-de-L'Ile-De-Montreal, Montreal, Quebec, Canada
- University Hospital Centre Zagreb, Zagreb, Croatia
- Humanitas, Milan, Italy
Who to contact
Adam Kinnaird, MD, PhD · 780-407-5800 · ask@ualberta.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT05558241.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.