Personalized B-fructan Diet in Inflammatory Bowel Disease Patients
Recruiting now NCT05615779
Run by University of Manitoba · for 6 to 39 · All sexes · accepts healthy volunteers
What this study is about
This study aims to examine patient tolerability of personalized dietary fibre consumption recommendations (high-pectin diet versus high-B-fructan diet based on personalized responses), provided by an IBD dietician, based on our novel translational research findings.
Who can join (things the study team will check)
✅ You may be able to join if…
- Children (age 6-17) or young adults (age 18-39).
- Known or suspected UC or IBDU [there will be 2 control group: non-IBD (undergoing colonoscopy but found not to have IBD; and healthy (no GI symptoms, so not required to have colonoscopy; could be family members)]
- For UC: Remission-mild-moderate disease: Mayo score <10
- Clinical indication for sedated colonoscopy
- Disease location: E2-E4
- Stable treatment (not on steroids; biologics or immunomodulator not changed in last month)
- High likelihood that patients will be able to collect all samples and provide all data
🚫 You may not be able to join if…
- Use of antibiotics for a week or more over the last 3 months
- Use of probiotics or prebiotics at pharmacological doses (adding fibre sources to food or probiotics in yogurt, for example, are allowed)
- History of abdominal surgery, including appendectomy
- Documented enteric infection during the 3 months prior to endoscopy
- Presence of non-IBD bowel conditions (e.g., celiac), anatomical or mucosal abnormalities, motility disorder
- Presence of a systemic disease requiring treatment (cancer, ischemic heart disease, kidney failure, etc)
- Proctitis (E1)
- Systemic steroids (above 10 mg/day of Prednisone)
- Topical therapy within 1 week of endoscopy
- Recent change in IBD treatment (started biologics or IM over the last month)
- Pregnancy or planning to become pregnant during the study
- Inability to understand or sign the consent
Where this trial is running
- University of Alberta Hospital, Edmonton, Alberta, Canada
- Health Sciences Centre Hospital, Winnipeg, Manitoba, Canada
Who to contact
Heather Armstrong, MSc, PhD · 2047893815 · heather.armstrong@umanitoba.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT05615779.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.
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