VIrtual Care To Improve Outcomes and RecoverY From Heart Failure Hospitalization

What this study is about

The clinic visits (intervention) will continue for 90 days, which represents the follow-up period for the primary medication and health status outcomes. The co-primary clinical outcomes will be obtained at 180 days.

Who can join (things the study team will check)

✅ You may be able to join if…

• Are being discharged after hospitalization or urgent visit for HF as
  • a primary diagnosis or
  • significant complication (prolonging length of stay) of another diagnosis OR Have been referred for an initial consult at a cardiology clinic within 1 week of hospitalization or urgent visit for HF as a primary or secondary diagnosis, as described above.
• Have left ventricular ejection fraction (LVEF) < 50% within the preceding 3 months.
• Have NT-proBNP of > 900 pg/ml during hospital admission or within 7 days after discharge from the ED
• Have a mailing address for patient or caregiver
• Provide verbal consent

🚫 You may not be able to join if…

• Died or left hospital before medically advised hospital discharge
• Unable to self-assess or communicate symptoms (e.g. clinically evident dementia)
• Unable to engage with digital health technology or follow up
• Severe valve disease
• Recipient of or on waiting list for LVAD or cardiac transplant
• Complex congenital heart disease, hypertrophic obstructive cardiomyopathy, or amyloid cardiomyopathy
• Severe lung disease with symptoms on minimal exertion, forced expiratory volume during 1 second (FEV1) < 1 litre, severe pulmonary hypertension with RVSP > 60 mm Hg, or on home oxygen
• Severe kidney disease (persistent eGFR < 30 mL/min/1.73m2)
• Active malignancy
• Receiving palliative care or expected life expectancy < 6 months

Where this trial is running

• St. Joseph's Healthcare Hamilton, Hamilton, Onatrio, Canada
• Hamilton General Hospital, Hamilton, Ontario, Canada
• Juravinski Hospital Cancer Centre, Hamilton, Ontario, Canada
• Thunder Bay Regional Health Sciences Centre, Thunder Bay, Ontario, Canada
• Unity Health Toronto, Toronto, Ontario, Canada
• Fattouma Bourguiba Hospital, Monastir, Tunisia
• Hedi Chaker Hospital, Sfax, Tunisia
• Sahloul Hospital, Sousse, Tunisia
• Military Hospital, Tunis, Tunisia

Who to contact

Harriette GC Van Spall, MD MPH · (905) 521-2100 · Harriette.VanSpall@phri.ca

It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT05724433.