Brain, Psychological and Epigenetic Determinants for Optimizing the Treatment of Chronic Low Back Pain
Recruiting now NCT05963451
Run by Université de Sherbrooke · for 18 to 75 · All sexes
What this study is about
The goal of this observational study is to better understand the role of the brain in chronic low back pain patients.
Who can join (things the study team will check)
✅ You may be able to join if…
- Low back pain (≥ 6 months) with or without pain radiating to the legs or radiating to the neck
- Positive medial branch blocks, suggesting that the pain originates from the lumbar facet joints
- Average pain intensity of ≥ 3/10 in the 24-hour period before the initial visit
- Pain primarily localized in the lower back
🚫 You may not be able to join if…
- Inadequate pain relief or relief of less than three months following selective thermoablation of medial lumbar branches by radiofrequency
- Neurological, cardiovascular, or pulmonary disorders
- Comorbid pain syndrome
- History of surgical intervention in the back
- A corticosteroid infiltration within the past year
- Pregnancy (current or planned during the course of the study)
- Contra-indication to Magnetic Resonance Imaging (MRI)
Where this trial is running
- Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (CRCHUS), Sherbrooke, Quebec, Canada
Who to contact
Pascal Tétreault, PhD · 819-346-1110 · pascal.tetreault@usherbrooke.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT05963451.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.
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