Transitioning to Home or In-center Dialysis

What this study is about

For people with advanced kidney disease, deciding which type of dialysis is best can be challenging. Studies have shown that quality of life is very important to patients. It is thought that the quality of life of people receiving their dialysis at home may be better than the one of people receiving dialysis in a hospital. However, how the start of dialysis changes the quality of life of people who choose home dialysis in comparison to people choosing dialysis in a hospital is still unknown. TRANSIT-CARE is a prospective mixed methods study following adult with advanced kidney disease who progress to dialysis and receive home or hospital-based dialysis. This study aims to examine the trajectory and change in patients' quality of life and their frailty status (health, mobility and function) before start of dialysis and up to 12-month after start. Differences between people doing home dialysis and hospital-based dialysis will be assesses taking into account people's characteristics including their gender and socio-demographics characteristics. The study will include questionnaires to measure quality of life and tools to evaluate frailty. Additionally, semi-structured interviews will be done with a diverse group of patients and caregivers before and after the initiation of dialysis to better understand their experience of transitioning to dialysis.

Who can join (things the study team will check)

✅ You may be able to join if…

• Adults followed in advanced CKD clinic,
• estimated glomerular filtration rate (eGFR) <12 mL/min/1.73m2 103,
• Have chosen their dialysis modality,
• Understand English or French.

🚫 You may not be able to join if…

• Orientation toward conservative treatment,
• Planned kidney transplantation < 6 months,
• Unable to provide consent due to severe cognitive or psychiatric disease,
• Previous treatment with dialysis > 3 months,
• Life expectancy < 6 months

Where this trial is running

• Hôpital Maisonneuve-Rosemont, Montreal, Quebec, Canada

Who to contact

Karine Chaussé · 514-252-3400 · karine.chausse.cemtl@ssss.gouv.qc.ca

It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT05989659.