An Extension to Assess the Effect of Expanded Dialysis on Patient Reported Symptoms Using LEVIL
Recruiting now NCT06032208
Run by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · for 18 and older · All sexes
What this study is about
Investigators know that many patients who are on dialysis suffer from burden of unwanted symptoms, which can affect quality of life. The understanding and treatment of symptom burden by healthcare providers is limited and should be recognized as a high priority in the care of the dialysis population. In this study, the investigators will be assessing symptom burden using the London Evaluation of Illness "LEVIL," an application based platform where patients self-report their symptoms with one to three hemodialysis treatments per week for 28 weeks. The investigators would like to compare the currently available dialyzer with a new dialyzer that is capable of removing solutes of higher molecular weight that may or may not cause patients to experience symptoms related to increased amounts of toxins in their blood.
Who can join (things the study team will check)
✅ You may be able to join if…
- Conventional thrice weekly HD schedule
- Must be on chronic hemodialysis for at least 3 months
- Age ≥18 years
- Willing and able to give informed consent
🚫 You may not be able to join if…
- Active infection (may enroll once infection is cleared)
- Patients receiving daily hemodialysis treatment
- Patients currently receiving Hemodiafiltration (HDF), Hemofiltration (HF) or Isolated ultrafiltration (ISO UF) more than once in three months
- Visual impairment
- History of neurocognitive impairment
- History of stroke (CVA)
Where this trial is running
- Seven Oaks Hospital Chronic Disease Innovation Centre Inc. (CDIC), Winnipeg, Manitoba, Canada
- QEII Health Sciences Centre, Nova Scotia Health, Halifax, Nova Scotia, Canada
- Victoria Hospital, London Health Sciences Centre, London, Ontario, Canada
- Westmount Kidney Care Centre, London, Ontario, Canada
Who to contact
Christopher McIntyre, MBBS DM · 5196858500 · Christopher.McIntyre@lhsc.on.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT06032208.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.