Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus

What this study is about

This study aims to investigate the feasibility and effectiveness of a cognitive behavioral coping skills program, Treatment and Education Approach for Childhood-onset Lupus (TEACH), for youth with cSLE when integrated into medical care. This TEACH program aims to teach participants skills in order to cope with fatigue, pain, and depressive symptoms--symptoms that commonly affect adolescents and young adults with lupus.

Who can join (things the study team will check)

✅ You may be able to join if…

• be diagnosed with cSLE, meeting the revised American College of Rheumatology Classification Criteria for SLE by age 18 years
• be between the ages of 12 and 22 years
• in recognition of the heterogeneity of cSLE symptoms, have elevations in fatigue (i.e., T scores ≥60; or at least moderate symptoms, on the PROMIS measure) OR depressive symptoms (≥5 on the PHQ-9, T Score ≥ 60 on the BDI or CDI II ), OR pain (i.e., average pain ≥3 out of 10 on the Pain VAS)
• have English language proficiency (their primary caregiver can have English or Spanish language proficiency for the child to enroll)
• those under age 18 years (US), or 16 years (Canada) must have a consenting caregiver

🚫 You may not be able to join if…

• other chronic medical conditions (e.g., juvenile arthritis)
• a documented developmental delay, severe cognitive impairment, or thought disorder
• an untreated major psychiatric illness (e.g., bipolar disorder, psychosis, severe depression (PHQ9 score ≥21, BDI/CDI II > 90) or active suicidal ideation (SI), based on the Pediatric Health Questionnaire (PHQ-9) items plus clinical interview; see Measures section)

Where this trial is running

• University of Alabama Birmingham Hospital, Birmingham, Alabama, United States
• Children's Hospital of New Orleans/ Tulane University, New Orleans, Louisiana, United States
• Helen Devos Children's Hospital, Grand Rapids, Michigan, United States
• Montefiore Medical Center, The Bronx, New York, United States
• Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
• Seattle Children's Hospital, Seattle, Washington, United States
• The Hospital for Sick Children, Toronto, Ontario, Canada

Who to contact

Jocelyn S Zuckerman, BA · 9785051866 · zucker32@msu.edu

It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT06232304.