DETECTion of PeriOperative Atrial Fibrillation After Noncardiac Surgery

What this study is about

This is a multicentre prospective cohort study where patients will receive up to 14 days of continuous ECG monitoring by wearing a portable monitoring device, starting within 72 hours after noncardiac surgery.

Who can join (things the study team will check)

✅ You may be able to join if…

• Had undergone noncardiac surgery within the past 72 hours and requiring, or expected to require, at least one of the following:
  • an overnight hospital admission after surgery
  • day surgery that would result in a large enough physiological insult to be able to cause POAF. Procedures excluded include those that are conducted using local anesthesia alone, are less than 30 minutes in duration, and/or are judged to be of low physiologic insult by the local investigator.
• Have one of the following high-risk criteria;
  • age 55-64 years, and having either established cardiovascular disease, recent major vascular surgery, a CHA2DS2-VASc score ≥3, or an elevated postoperative troponin level;
  • age 65-74 years, and having either established cardiovascular disease, recent major vascular surgery, a CHA2DS2-VASc score ≥2, or an elevated postoperative troponin level; or
  • age ≥75 years;
• Provide written informed consent to participate.

🚫 You may not be able to join if…

• History of documented chronic (i.e., non-transient) AF before noncardiac surgery;
• Need for long-term systemic anticoagulation;
• Ongoing need for long-term dual antiplatelet treatment;
• Contraindication to oral anticoagulation;
• Severe renal insufficiency;
• Severe liver cirrhosis;
• Acute stroke in the past 14 days;
• Underwent cardiac surgery in the past 35 days;
• History of nontraumatic intracranial, intraocular, or spinal bleeding;
• Hemorrhagic disorder or bleeding diathesis;
• Known life expectancy <1 year due to concomitant disease;
• Women who are pregnant, breastfeeding, or of childbearing potential not taking effective contraception;
• Expected to be non-compliant with follow-up and/or device use;
• Known contact allergy to monitoring device and/or its peripheral components;
• Previously enrolled in DETECT-POAF.

Where this trial is running

• Hamilton General Hospital, Hamilton, Ontario, Canada
• St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada
• Juravinski Hospital, Hamilton, Ontario, Canada
• London Health Sciences Centre - University Hospital, London, Ontario, Canada
• Niagara Health System - St. Catharine's Site, St. Catharines, Ontario, Canada
• Hôpital Fleurimont du Centre hospitalier universitaire de Sherbrooke, Sherbrooke, Quebec, Canada

Who to contact

Vitheya Thanabalan · +1 905-296-2710 · detectpoaf@phri.ca

It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT06519747.