Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.

What this study is about

The purpose of this study is to compare whether the FDA and Health Canada approved microUS is as effective as the currently used option (MRI) for imaging the prostate gland. Participants will be randomized into two groups to compare the imaging results of the current standard of care MRI and the new microUS. The study is looking to identify the most effective imaging modality to help guide whether you progress to have a prostate biopsy.

Who can join (things the study team will check)

✅ You may be able to join if…

• Male sex;
• Age 50-70;
• PSA 3-20 and/or abnormal DRE;
• Biopsy naïve.

🚫 You may not be able to join if…

• Prior personal history of prostate cancer;
• Prior prostate imaging using microUS or MRI;
• Contraindication to microUS or MRI;
• Testosterone replacement therapy within last 12 months; or
• Androgen deprivation therapy within last 12 months.

Where this trial is running

• University of California, Los Angeles (UCLA), Los Angeles, California, United States
• UT Southwestern Medical Center, Dallas, Texas, United States
• University of Alberta, Edmonton, Alberta, Canada
• University of British Columbia, Vancouver, British Columbia, Canada
• Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
• CIUSSS du Nord-de-l'Île-de-Montréal, Montréal, Quebec, Canada
• CH de Martigues, Martigues, France
• Vestfold Hospital Trust, Tønsberg, Norway
• Urologia Clinica Bilbao, Bilbao, Spain

Who to contact

Stacey Broomfield, PhD · +1-780-407-5800 · sbroomfi@ualberta.ca

It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT06626022.