A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Recruiting now Phase 2 NCT06635148
Run by Janssen Research & Development, LLC · for 60 and older · All sexes
What this study is about
The purpose of this study is to assess the long-term safety and tolerability after an intravitreal injection (a shot of medicine into the eye) of JNJ-81201887 administered in parent clinical studies.
Who can join (things the study team will check)
✅ You may be able to join if…
- Participants who were enrolled and received treatment with JNJ-81201887 or sham in a parent clinical study (81201887MDG2001, 81201887MDG1003)
- Females (women of childbearing potential), male participants, and partners of male participants will not be required to use contraception in this LTE study
- Must sign an informed consent form (ICF) indicating that participant understands the purpose of, and procedures required for, the study and is willing to participate in the study. The ICF may be signed by an impartial witness and/or legally designated representative depending on national/local regulations
🚫 You may not be able to join if…
- There are no exclusion criteria for this LTE study
Where this trial is running
- Retina Associates Southwest PC, Tucson, Arizona, United States
- Retina Consultants of Orange County, Fullerton, California, United States
- Shiley Eye Institute Jacobs Retina Center, La Jolla, California, United States
- California Retina Consultants, Oxnard, California, United States
- California Eye Medical Specialists, Pasadena, California, United States
- Retina Consultants San Diego, Poway, California, United States
- Bay Area Retina Associates, Walnut Creek, California, United States
- Retina Group of Florida, Fort Lauderdale, Florida, United States
- VitreoRetinal Associates, PA, Gainesville, Florida, United States
- Retina Specialty Institute, Pensacola, Florida, United States
- Retina Vitreous Associates of Florida, St. Petersburg, Florida, United States
- Georgia Retina, Marietta, Georgia, United States
+ 92 more sites.
Who to contact
Study Contact · 844-434-4210 · Participate-In-This-Study1@its.jnj.com
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT06635148.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.
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