Improving Health Outcomes With Kefir

What this study is about

The purpose of the study is to ascertain whether traditional kefir not only enhances vascular health but also contributes to improved immune outcomes in both male and female participants at higher risk or living with Type 2 Diabetes (T2D) after 12 weeks of treatment.

Who can join (things the study team will check)

✅ You may be able to join if…

• females and males (24-70 years old) living in Edmonton (or Edmonton area/driving distance);
• overweight or obesity (BMI >25 Caucasian, >23 Asian);
• at higher risk of T2D (fasting blood glucose ≥ 5.6 - 6.9 mmol/L or/and HbA1C ≥ 5.5 - 6.4%); or
• with diagnosis of T2D (fasting blood glucose ≥ 7.0 mmol/L or/and HbA1C ≥ 6.5%).

🚫 You may not be able to join if…

• a usual high intake (maximum intake 3 servings/week) of fermented foods excluding cheese (i.e., kefir, kombucha, kimchi, etc.) for the past 3 months;
• gastrointestinal (GI) disorders of any kind;
• being pregnant or breastfeeding;
• monogenic dyslipidemias and endocrine disorders except for diabetes;
• use of medications within the last 3 months (i.e., antibiotics or antifungals, corticosteroids, methotrexate, or immunosuppressive cytotoxic agents);
• any health conditions deemed to interfere with primary outcomes at the investigator's discretion (e.g., kidney disease, liver disease, cancer, GI surgery, heavy alcohol consumption, etc.);
• having a pacemaker or any electrical medical device that prevents the individual from undergoing the bioelectrical impedance analysis bioimmunoassay (BIA) test."

Where this trial is running

• University of Alberta, Edmonton, Alberta, Canada

Who to contact

Paulina Aldana Hernandez, PhD · 780-492-9506 · paldana@ualberta.ca

It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT06695221.