Supplementing Neuro-Energy to Aid Cognition
Opening soon NCT06767124
Run by University of Pennsylvania · for 21 and older · All sexes · accepts healthy volunteers
What this study is about
It is projected that by 2030, one in every five Americans will be of retirement age, and this demographic shift is expected to result in more people suffering from dementia. A key feature of the brain is its need for a constant supply of glucose and oxygen to meet the high energy costs of mental activity. This study aims to develop clinically practical, noninvasive imaging methods based on combined positron emission tomography and magnetic resonance imaging to assess brain energy in order to better understand how this critical component of brain health is impacted by aging.
Who can join (things the study team will check)
Inclusion Criteria - Healthy Participants: Males and females, Age 21 - 80 years, BMI of 18.5-30 Inclusion Criteria - Alzheimer's Disease Participants: Positive amyloid and tau biomarkers (as noted by PET imaging, cerebrospinal fluid or blood), Mild cognitive impairment or mild-to-moderate dementia, BMI of 18.5-30 Exclusion Criteria: Contraindications to MRI (claustrophobia, metal implants, pacemakers, etc.), Pregnant or breastfeeding women, Neurological disease (healthy participants only), Mental illness, Overt cardio- or neurovascular disease, Recent participation in any procedure(s) involving radioactive agents…
Where this trial is running
- Lawson Research Institute, London, Ontario, Canada
Who to contact
Keith St Lawrence, PhD · (519) 646-6100 · kstlawr@uwo.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT06767124.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.