Internet-Delivered Cognitive Behaviour Therapy for Women with Perimenopausal Anxiety

What this study is about

The goal of this clinical trial is to design an online Cognitive Behavioural Therapy (CBT) and Acceptance Commitment Therapy (ACT) program and to learn if it can treat anxiety in women transitioning into menopause (perimenopause). The main questions it aims to answer are: * Is our online psychotherapy program a practical and acceptable means of managing anxiety during perimenopause? * Does our online psychotherapy program work in improving anxiety levels during perimenopause? Participants will participate in weekly e-CBT module sessions tailored to perimenopausal anxiety and will be given weekly feedback on assignments from trained care providers through a secure online platform. Participants will complete questionnaires at the beginning, middle, and at end of the study, as well as at the three and six-month follow-up.

Who can join (things the study team will check)

✅ You may be able to join if…

• In perimenopausal staging (as defined by the STRAW +10 criteria)
• Assigned female at birth
• Diagnosis of GAD according to DSM-5 by attending psychiatrist on research team
• Competence to consent to participate
• Ability to speak and read English
• Consistent and reliable access to the internet

🚫 You may not be able to join if…

• Undergone CBT or hormone therapy within the last 6 months will be excluded
• Active psychosis
• Acute mania
• Severe alcohol or substance use disorder
• Active suicidal or homicidal ideation

Where this trial is running

• Kingston General Hospital, Kingston, Ontario, Canada
• Nazanin Alavi, Kingston, Ontario, Canada

Who to contact

Nazanin Alavi, MD, FRCPC · 613-544-3310 · nazanin.alavitabari@kingstonhsc.ca

It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT06865066.