The Safety and Feasibility of Radiofrequency Ablation to Treat Low-risk Thyroid Cancer
Recruiting now NCT06929650
Run by University Health Network, Toronto · for 18 to 100 · All sexes · accepts healthy volunteers
What this study is about
The goal of this clinical trial is to test radiofrequency ablation (RFA) in thyroid cancers ≤2 cm in diameter. The main question it aims to answer is: • What is the feasibility of RFA use for low-risk thyroid cancers (≤2 cm)? Participants will undergo a set of pre-procedural scans of the target thyroid nodule and undergo the RFA procedure/intervention. Then, participants will partake in three follow-up appointments at 4 weeks, 6 months, and 12 months post-procedure as per standard of care.
Who can join (things the study team will check)
✅ You may be able to join if…
- Patients with:
- Nodule less than or equal to 2cm in size a. Specifically: Bethesda 5/6
- Their age is ≥18 years and ≤100 years
- Able to provide written consent
- Able to attend required follow-ups as per the protocol
🚫 You may not be able to join if…
- Patients <18 years old
- Pregnant women
- Any concern for invasive or metastatic thyroid cancer
- Previously treated for thyroid cancer
Where this trial is running
- University Health Network, Toronto, Ontario, Canada
Who to contact
Jesse Pasternak · (416) 340-4792 · jesse.pasternak@uhn.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT06929650.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.