Enhancing Patient Comfort and Reducing Anxiety During Flexible Cystoscopy and Bladder Instillation in Bladder Cancer Patients: A Randomized Controlled Trial and Observational Study
Opening soon NCT07204301
Run by Western University, Canada · for 18 and older · All sexes
What this study is about
The goal of this clinical trial is to learn if certain comfort-enhancing interventions can reduce pain and anxiety during flexible cystoscopy and bladder instillation in patients with bladder cancer. The main questions it aims to answer are: * Do these interventions reduce patient-reported anxiety during the procedure? * Do these interventions reduce patient-reported pain or discomfort during the procedure? Researchers will compare patients receiving comfort interventions (such as timing of anesthetic gel, calming music, or visual distraction) to those receiving standard care to see if these changes improve patient experience. Participants will: * Undergo a flexible cystoscopy or bladder instillation as part of their usual care * Be randomly assigned to receive one or more comfort interventions, or standard care * Complete short questionnaires about their pain, comfort, and anxiety
Who can join (things the study team will check)
✅ You may be able to join if…
- Age ≥ 18 years
- Diagnosis of bladder cancer undergoing diagnostic/surveillance flexible cystoscopy or intravesical bladder instillation in the outpatient urology clinic
- Able to provide informed consent
🚫 You may not be able to join if…
- Individuals unable to provide informed consent (e.g., diminished or fluctuating capacity).
- Individuals unable to communicate verbally with study staff (e.g., severe speech/hearing impairment without assistive support available).
- Individuals with severe cognitive impairment or acute distress at the time of approach that prevents informed consent.
- Individuals with known hypersensitivity or allergy to lidocaine, topical anesthetic gel, or any components used in the procedure.
- Individuals for whom, in the opinion of the treating urologist, participation would pose undue clinical risk or interfere with urgent clinical care.
Where this trial is running
- Victoria Hospital - London Health Sciences Center, London, Ontario, Canada
Who to contact
Nicholas E Power, MD · 519-667-6787 · nicholas.power@lhsc.on.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT07204301.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.