Sensitivity to Ovarian Hormones and Depression in Adolescents
Opening soon NCT07317895
Run by University of Calgary · for 12 to 18 · Women
What this study is about
The goal of this observational study is to learn about the relationship between changes in ovarian hormones (estrogen and progesterone) and adolescent depression. The main question it aims to answer is: Can we identify a subset adolescents assigned female at birth with a history of depression who are particularly sensitive to changes in ovarian hormones? Participants will be monitoring daily absolute ovarian hormone levels at home using the Mira Analyzer and answer online survey questions about their mental health for 90 days.
Who can join (things the study team will check)
✅ You may be able to join if…
- Assigned female at birth, at least 1 year post-menarche, naturally cycling, history of depression or symptoms of depression, and able to read and write in English.
🚫 You may not be able to join if…
- Pregnant or taking any hormonal or cycle altering medications/devices.
Where this trial is running
- University of Calgary, Calgary, Alberta, Canada
Who to contact
Whitney Hindmarch, PhD · 587-534-7260 · whitney.hindmarch@ucalgary.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT07317895.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.