Efficacy of Biofeedback Training for Glaucoma

What this study is about

This randomized controlled clinical trial evaluates the efficacy of visual biofeedback training on visual function and quality of life in individuals with glaucoma. Glaucoma is a progressive optic neuropathy that can lead to irreversible vision loss, including impaired fixation stability, reduced retinal sensitivity, and decreased functional vision. Biofeedback training is a visual rehabilitation technique designed to help patients improve fixation stability and optimize use of remaining visual function by training eye movements toward retinal areas with better sensitivity. Seventy participants with glaucoma will be randomized to either a biofeedback training intervention group or a control group. Visual function outcomes, including fixation stability, retinal sensitivity, visual acuity, reading speed, contrast sensitivity, and quality of life, will be assessed at baseline and follow-up visits. This study aims to determine whether biofeedback training can improve visual function and quality of life in patients with glaucoma.

Who can join (things the study team will check)

✅ You may be able to join if…

• 18-95 years old.
• Glaucoma cases with adequate intraocular pressure control.
• Presence of paracentral scotomata within two degrees of fixation.
• Ability to follow instructions for biofeedback training.

🚫 You may not be able to join if…

• Prior or current low vision rehabilitation treatment.
• Ocular diseases or severe clinical conditions unrelated to glaucoma
• Media opacities that prevent reliable microperimetry testing in both eyes.
• Inability to perform study assessments or follow instructions for biofeedback training.

Where this trial is running

• University Health Network/ Toronto Western Hospital, Toronto, Ontario, Canada