A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative Colitis
Recruiting now Phase 2 NCT07470879
Run by Pfizer · for 2 to 11 · All sexes
What this study is about
The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in pediatrics participants (≥ 2 years up to \< 12 years of age). Participants who will complete the total 52-week treatment period will have the opportunity to continue in a Long-Term Extension (LTE) Period of up to 4 years (5 years after study enrollment).
Who can join (things the study team will check)
Inclusion criteria: Have a diagnosis of ulcerative colitis (UC) that is moderately to severely active Participants are permitted to be receiving a therapeutic dose of select UC therapies Exclusion criteria: Severe extensive colitis Diagnosis of Crohn's disease (CD) or indeterminate colitis or the presence or history of a fistula consistent with CD Diagnosis of microscopic colitis, ischemic colitis, or infectious colitis…
Where this trial is running
- Fink Children's Ambulatory Care Center, New York, New York, United States
- Kimmel Pavilion - NYU Langone, New York, New York, United States
- NYU Grossman School of Medicine, New York, New York, United States
- NYU Langone Health (Tisch Hospital), New York, New York, United States
- NYU Langone Inflammatory Bowel Disease Center, New York, New York, United States
- NYU Langone Radiology - Tisch Hospital, New York, New York, United States
- NYU Medical Science Building (MSB), New York, New York, United States
- The Children's Hospital at Westmead, Westmead, New South Wales, Australia
- Monash Health, Clayton, Victoria, Australia
- Perth Children's Hospital, Perth, Western Australia, Australia
- Health Sciences Centre Winnipeg, Winnipeg, Manitoba, Canada
- Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada
+ 30 more sites.
Who to contact
Pfizer CT.gov Call Center · 1-800-718-1021 · ClinicalTrials.gov_Inquiries@pfizer.com
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT07470879.
Verify everything on the official ClinicalTrials.gov record. Page updated September 2026.