Effect of Ambient Temperature on Blood Glucose and Insulin Absorption in Adults With Type 1 Diabetes

What this study is about

The goal of this clinical trial is to learn how different temperatures affect blood sugar levels in adults with type 1 diabetes. Climate change is causing more extreme hot and cold weather, and people with type 1 diabetes may be at higher risk during these temperature changes. The main questions it aims to answer are: * Do different temperatures (cold, normal, or hot) change blood sugar levels in people with type 1 diabetes? * How does temperature affect insulin absorption in the body? Researchers will compare three different temperature conditions to see how each affects blood sugar levels and insulin in the body. Participants will: * Complete a screening visit with body measurements and questionnaires * Attend 3 separate study visits, each in a different temperature setting: * Cold room (10°C/50°F) * Normal room temperature (23°C/73°F) * Hot and humid room (36°C/97°F with 65% humidity) * Sit for 2 hours in each temperature condition while researchers monitor their blood sugar, heart rate, and body temperature * Wear a continuous glucose monitor for 48-72 hours before each visit * Keep a diary of food, sleep, and activity for 24 hours before and after each visit Each temperature visit is separated by at least 3 days. The study helps researchers understand if people with type 1 diabetes need special guidance for managing their blood sugar during extreme weather.

Who can join (things the study team will check)

✅ You may be able to join if…

• Diagnosis of type 1 diabetes for more than 2 years
• Ability to provide verbal and written informed consent
• Ability to speak and understand French

🚫 You may not be able to join if…

• Recent and/or unstable health condition (less than 3 months) prior to enrolment
• Any viral infection at time of participation
• Chronic illness other than type 1 diabetes (for example: pulmonary disease, cardiovascular disease, cancer)
• Health condition not controlled by medication
• Pregnancy or breastfeeding (for female participants)
• Any other health condition deemed to pose undue health risks during participation in the study

Where this trial is running

• Institut de recherches cliniques de Montréal, Montreal, Quebec, Canada

Who to contact

Corinne Suppere, MSc · 514-987-5597 · corinne.suppere@ircm.qc.ca

It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT07491133.