Evaluating the Feasibility of Prehabilitation Delivery Models for Patients Preparing for Ovarian Cancer Surgery

What this study is about

The goal of this clinical trial is to learn whether high-dose multimodal prehabilitation, delivered either in person or remotely with coaching and web application support, is feasible and acceptable for women preparing for ovarian cancer surgery. It will also examine which delivery model patients prefer and the factors influencing patient preferences. The main questions ADAPT-OC aims to answer are: 1. Can participants achieve the prescribed aerobic exercise target of at least 10 MET-hours per week before surgery? 2. Do patients prefer in-person prehabilitation, remote prehabilitation, or education-only care, and what factors influence that preference? The researchers will compare in-person prehabilitation, remote prehabilitation, and education-only care to see which delivery approach is most feasible, acceptable, and practical for patients with suspected ovarian cancer. Participants will: * Choose their preferred study group, or be randomly assigned if they have no preference * Complete physical assessments, questionnaires, and interviews at baseline, 1-3 days before surgery, and 4 weeks after surgery * If assigned to a prehabilitation group, complete aerobic exercise, protein supplementation, and daily breathing exercises before surgery * Attend weekly coaching sessions with a trained prehabilitation coach * Use the KingstonPrehab web application to track exercise, nutrition, breathing practice, and progress toward activity goals

Who can join (things the study team will check)

✅ You may be able to join if…

• Female
• Aged ≥18 years
• Scheduled for cytoreductive surgery for an ovarian mass suspected or confirmed of cancer
• Surgery planned ≥3 weeks from time of booking
• No contraindications to exercise on the CSEP Get Active Questionnaire
• Able to provide written informed consent
• Able to understand and communicate in English

🚫 You may not be able to join if…

• Pregnancy
• Surgery scheduled <3 weeks from booking
• Receiving neoadjuvant chemotherapy
• Positive contraindications to exercise on the CSEP Get Active Questionnaire
• End-stage or advanced renal disease limiting safe protein supplementation
• Malnutrition as assessed by a registered dietician

Where this trial is running

• Kingston Health Sciences Centre, Kingston, Ontario, Canada

Who to contact

Deborah DuMerton · 613-484-7322 · deborah.dumerton@kingstonhsc.ca

It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT07609082.