Rhythm Psychophysics With Parkinson's Patients
Opening soon NCT07647913
Run by McMaster University · for 40 to 80 · All sexes
What this study is about
The goal of this interventional study is to understand how the rhythmic abilities of individuals in the early stages of Parkinson's Disease (PD) are impacted by their levels of dopamine. The main questions it aims to answer are: * Does dopamine shelter the ability to generate and maintain a regular tapping rhythm in the presence of disrupting sensory information? * Does dopamine allow the adaptation of tapping speed in the presence of changing sensory information? * Is the engagement of the motor system useful to improve the detection of changes in the tempo of sensory information? Participants will be asked to perform a battery of simple rhythmic tasks On and Off medication to evaluate the effect of dopamine on their rhythmic skills.
Who can join (things the study team will check)
✅ You may be able to join if…
- Parkinson's Disease diagnostic
- Stage 1 or 2 Hoenh-Yahr scale
- Taking immediate-release Levodopa
- MoCA score of 26 or above
🚫 You may not be able to join if…
- Dementia
- Other neurodegenerative disease
- History of substance abuse
- History of hearing disorders
- History of neuropsychiatric disease
Where this trial is running
- Psychology Building, Hamilton, Ontario, Canada
Who to contact
Jonathan Cannon, Dr · (905) 531-6902 · cannoj9@mcmaster.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT07647913.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.