Feasibility of a Community-Integrated Isometric Handgrip Exercise Program and Its Preliminary Effects on Blood Pressure and Cognitive Function in Older Adults
Opening soon NCT07648498
Run by McMaster University · for 65 and older · All sexes
What this study is about
The goal of this clinical trial is to evaluate whether a short, supervised isometric handgrip exercise program is feasible and acceptable for older adults with elevated blood pressure or hypertension. It will also explore whether this type of exercise may improve blood pressure and cognitive function. The main questions it aims to answer are: * Is this handgrip exercise program practical and acceptable for older adults to participate in within a community exercise setting? * Does participation in the program lead to changes in blood pressure and cognitive function? Researchers will compare two handgrip devices to determine whether the method of delivering the exercise influences feasibility and outcomes. Participants will: * Be randomly assigned to use one of two handgrip devices. * Complete supervised exercise sessions twice per week for 4 weeks. * Perform brief handgrip contractions at a set intensity during each session. * Complete blood pressure and cognitive assessments before and after the program.
Who can join (things the study team will check)
✅ You may be able to join if…
- 65 years of age or older
- Currently attending the Physical Activity Centre of Excellence at McMaster University
- English speaking
- Diagnosed with hypertension or elevated blood pressure
🚫 You may not be able to join if…
- Current or prior participation in chronic isometric exercise
- Unstable angina.
- Uncontrolled hypertension
- Uncontrolled heart failure and/or arrhythmias
- Recent myocardial infarction or electrocardiography changes
- Complete heart block
- Carpal tunnel syndrome
- Arthritis that may be aggravated by handgrip exercise
- Changes to the type and/or dose of blood pressure medications within 3 months of starting the study.
Where this trial is running
- NeuroFit Lab, Ivor Wynne Centre, McMaster University, Hamilton, Ontario, Canada
- Physical Activity Centre of Excellence, Ivor Wynne Centre, McMaster University, Hamilton, Ontario, Canada
Who to contact
Ava Neely, BHK · 4039735863 · neelya@mcmaster.ca
It's completely normal to call and ask questions before deciding anything. Mention the study ID: NCT07648498.
Verify everything on the official ClinicalTrials.gov record. Page updated July 2026.