Essais cliniques près de Toronto : maladie de parkinson

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

Recruiting nowPhase 3174 sites

The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics (PK) of prasinezumab compared with placebo in participants with early-stage Parkinson's disease (PD) on stable symptomatic monotherapy with levodopa.

Parkinson's Foundation PD GENEration Genetic Registry

Recruiting now56 sites

Development of a central repository for PD-related genomic data for future research.

A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications

Recruiting now26 sites

This is an observational study in which data are collected and studied from Parkinson's disease patients who have movement symptoms despite taking standard Parkinson's medications. In observational studies, observations are made without any…

Speech Learning and Speech Production in Parkinson's Disease

Recruiting now1 site

Parkinson's disease, a common movement disorder that results from a breakdown in the brain, often leads to challenges with talking, but less is known about the relationship between difficulties with talking and difficulties with learning to…

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

Recruiting now85 sites

The purpose of this registry is to compile characteristics of world-wide outcomes for the use of Boston Scientific's commercially available Vercise DBS System in the treatment of Parkinson's disease. The utilization of Image Guided Program…

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Recruiting nowPhase 270 sites

The goal of this Phase 2 clinical trial is to investigate the efficacy and safety of NEU-411 in men and women aged 40-80 years with early Parkinson's Disease (PD) who have predicted elevations in the activity of the "leucine-rich repeat kin…

Rhythm Psychophysics With Parkinson's Patients

Opening soon1 site

The goal of this interventional study is to understand how the rhythmic abilities of individuals in the early stages of Parkinson's Disease (PD) are impacted by their levels of dopamine. The main questions it aims to answer are: * Does dop…

LIFUS For Neurological Disorders

Recruiting now1 site

Low intensity focused ultrasound (LIFUS) has the potential to be used as a means of non-invasive neuro-modulation. To this day, the use of LIFUS is under investigation. Studies in healthy subjects have shown that application of LIFUS to the…

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

Recruiting now50 sites

The Parkinson Progression Marker Initiative (PPMI) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's d…

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

Opening soon2 sites

The goal of this clinical trial is two-fold. First to investigate the feasibility of whether a remotely administered smartphone app can increase the volume and intensity of physical activity in daily life in individuals with a LRRK2 G2019S …

Questions fréquentes

Comment trouver un essai clinique (maladie de parkinson) près de chez moi au Canada ?

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